Asthma is a major public health problem worldwide and is associated with excess morbidity, mortality, and economic costs associated with lost productivity. The National Asthma Education and Prevention Program has released the 2020 Asthma Guideline Update with updated evidence-based recommendations for tr...
Rochwerg, Bram;
Agoritsas, Thomas;
Lamontagne, François;
Leo, Yee-Sin;
Macdonald, Helen;
Agarwal, Arnav;
Zeng, Linan;
Lytvyn, Lyubov;
Appiah, John Adabie;
Amin, Wagdy;
Arabi, Yaseen;
Blumberg, Lucille;
Burhan, Erlina;
Bausch, Frederique;
Calfee, Carolyn S;
Cao, Bin;
Cecconi, Maurizio;
Chanda, Duncan;
Cooke, Graham;
Du, Bin;
Dunning, Jake;
Geduld, Heike;
Gee, Patrick;
Hashimi, Madiha;
Hui, David S;
Kabra, Sushil;
Kanda, Seema;
Kawano-Dourado, Leticia;
Kim, Yae-Jean;
Kissoon, Niranjan;
Kwizera, Arthur;
Laake, Jon Henrik;
Machado, Flavia R;
Mahaka, Imelda;
Manai, Hela;
Mino, Greta;
Nsutebu, Emmanuel;
Pshenichnaya, Natalia;
Qadir, Nida;
Sabzwari, Saniya;
Sarin, Rohit;
Sharland, Michael;
Shen, Yinzhong;
Ranganathan, Shalini Sri;
Souza, Joao;
Ugarte, Sebastian;
Venkatapuram, Sridhar;
Dat, Vu Quoc;
Vuyiseka, Dubula;
Wijewickrama, Ananda;
Maguire, Brittany;
Zeraatkar, Dena;
Bartoszko, Jessica;
Ge, Long;
Brignardello-Petersen, Romina;
Siemieniuk, Reed;
Guyatt, Gordon;
Diaz, Janet;
Jacobs, Michael;
Vandvik, Per Olav.
What is the role of drug interventions in the treatment of patients with covid-19? The latest version of this WHO living guidance focuses on remdesivir, following the 15 October 2020 preprint publication of results from the WHO SOLIDARITY trial. It contains a weak or conditional recommendation against th...
Falavigna, Maicon;
Colpani, Verônica;
Stein, Cinara;
Azevedo, Luciano César Pontes;
Bagattini, Ângela Maria;
Brito, Gabriela Vilela de;
Chatkin, José Miguel;
Cimerman, Sérgio;
Corradi, Mirian de Freitas Dal Ben;
Cunha, Clóvis Arns da;
Medeiros, Flávia Cordeiro de;
Oliveira Júnior, Haliton Alves de;
Fritscher , Leandro Genehr;
Gazzana, Marcelo Basso;
Graf, Débora Dalmas;
Marra, Lays Pires;
Matuoka , Jéssica Yumi;
Nunes, Michelle Silva;
Pachito, Daniela Vianna;
Pagano, Cássia Garcia Moraes;
Parreira, Patrícia do Carmo Silva;
Riera, Rachel;
Silva Júnior, Amilton;
Tavares, Bruno de Melo;
Zavascki, Alexandre Prehn;
Rosa, Régis Goulart;
Dal-Pizzol, Felipe.
Different therapies are currently used, considered, or proposed for the treatment of COVID-19; for many of those therapies, no appropriate assessment of effectiveness and safety was performed. This document aims to provide scientifically available evidence-based information in a transparent interpretatio...
Infecciones por Coronavirus/tratamiento farmacológico,
Aminoquinolinas/uso terapéutico,
Oseltamivir/uso terapéutico,
Lopinavir/uso terapéutico,
Ritonavir/uso terapéutico,
Corticoesteroides/uso terapéutico,
Heparina/uso terapéutico,
Antibacterianos/uso terapéutico,
Betacoronavirus/efectos de los fármacos,
Neumonía Viral/tratamiento farmacológico,
Pandemias/prevención & control
Desde la publicación de la primera edición de la Guía en 2013, se ha generado mucha información en torno al tratamiento de la colitis ulcerosa, y se han introducido nuevos fármacos y protocolos de actuación. La práctica clínica ha variado substancialmente, lo que justifica nuevas aproximaciones y...
Baddini-Martinez, Jose;
Ferreira, Juliana;
Tanni, Suzana;
Alves, Luis;
Cabral Junior, Benedicto Francisco;
Carvalho, Carlos Roberto Ribeiro;
Cezare, Talita;
Costa, Claudia da;
Gazzana, Marcelo;
Jezler, Sergio;
Adib Kairalla, Ronaldo;
Kawano-Dourado, Leticia;
Lima, Mariana Silva;
Mancuzo, Eliane;
Moreira, Maria Auxiliadora Carmo;
Rodrigues, Marcelo Palmeira;
Rodrigues, Silvia Carla Sousa;
Rubin, Adalberto Sperb;
Lopes, Rogerio;
Steidle, Leila John Marques;
Storrer, Karin;
Baldi, Bruno Guedes.
Idiopathic pulmonary fibrosis (IPF) is a form of chronic interstitial lung disease of unknown cause, which predominantly affects elderly men who are current or former smokers. Even though it is an uncommon disease, it is of great importance because of its severity and poor prognosis. In recent decades, s...
